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What Is Endophthalmitis and How to Manage It
What Is Endophthalmitis? Endophthalmitis is a rare but serious eye condition that can lead to vision loss if not promptly treated. This infection targets the interior structures of the eye, causing inflammation and potential damage. Understanding the symptoms, causes, treatment…
Understanding Factors Behind Corneal Transplant Failures
Corneal transplantation, also known as keratoplasty, is a common procedure performed to restore vision in individuals with corneal diseases or injuries. While the majority of corneal transplants are successful, a significant number of cases experience complications or ultimately fail. This…
What Is Corneal Opacity? | OBN
Corneal opacity refers to the clouding or loss of transparency in the cornea, the clear, dome-shaped front part of the eye. It can significantly impair vision and lead to various visual disturbances. This comprehensive article aims to provide a detailed…
Comprehensive Eye Drop Recall List for 2023
Since February 2023, the FDA and various companies have been actively initiating recalls of eye drops and ointments due to concerns about potential bacterial contamination. The recalls, motivated by the risk of tainted products, have been steadily increasing, underscoring the…
Astellas Signs Ophthalmic Gene Therapy Deal with 4DMT
Astellas Pharma has signed a license agreement that grants them the rights to utilize the intravitreal retinotropic R100* vector, developed by 4D Molecular Therapeutics (4DMT). This agreement enables Astellas to target one specific genetic target associated with rare monogenic ophthalmic…
Waterloo University’s Drug for AMD and DME
Researchers have successfully developed a groundbreaking synthetic protein to treat macular degeneration and other currently incurable eye diseases leading to blindness in millions of individuals. This pioneering drug, currently undergoing human trials, is the first of its kind. With over…
Novartis to Halt Development of GA Gene Therapy
After observing discouraging phase 2 clinical data, Novartis has opted to terminate the clinical advancement of its geographic atrophy gene therapy candidate GT005, a product it acquired through the acquisition of Gyroscope Therapeutics. The announcement was officially disseminated by investment…
What Is Bull’s Eye Maculopathy and How to Manage It
What Is Bull’s Eye Maculopathy? Bull’s Eye Maculopathy is a specific form of retinal disease characterized by changes in the pigmentation of the macular region of the retina, often presenting as a ‘bull’s eye’ pattern. The macula is the central…
Iveric Bio’s Izervay for Geographic Atrophy Approved by FDA
Parent company Astellas Pharma announced that Iveric Bio has received FDA approval for Izervay (avacincaptad pegol intravitreal solution) to treat geographic atrophy (GA) secondary to age-related macular degeneration (AMD). As a new complement C5 inhibitor, Izervay stands out as the sole…
Best Treatment for Uveitic Macular Edema Identified
Repeat corticosteroid injections were found to be more effective in improving vision for individuals with persistent or recurrent uveitis-related macular edema compared to methotrexate or ranibizumab intravitreal injections, according to a recent clinical trial. The corticosteroid treatment exhibited superior results…