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Regeneron’s High-Dose Aflibercept Receives FDA Approval
Regeneron has received FDA approval for Eylea HD (aflibercept 8 mg) in a significant development anticipated to substantially extend dosing intervals for patients with retinal diseases such as wet age-related macular degeneration (AMD), diabetic macular edema (DME), and diabetic retinopathy (DR).…
FDA Rejects Lytenava by Outlook Therapeutics for Wet AMD
Outlook Therapeutics announced that the FDA has issued a complete response letter (CRL) regarding the company’s Biologics License Application (BLA) for ONS-5010 (Lytenava). ONS-5010 is an investigative ophthalmic formulation of bevacizumab aimed at treating wet AMD. While the FDA recognized…
AsclepiX Therapeutics Raises $10M for Wet AMD Study
AsclepiX Therapeutics announced the completion of a $10 million Series A-3 financing aimed at advancing the clinical development of its leading candidate, AXT107 (gersizangitide), in patients diagnosed with wet AMD. “With the completion of this round, we are excited to…
Eye Drops Could Revolutionize Wet AMD Therapy
A novel compound, created at the University of Illinois Chicago, holds the potential to provide an alternative to injections for the vast population suffering from an eye condition leading to blindness. This condition, known as wet age-related macular degeneration (AMD),…
Scientists Develop AI to Help Doctors Pick Best IOL Option
Scientists have developed computer models of patients’ eyes to determine the most suitable intraocular lenses and to offer patients a visual simulation of their expected vision with these lenses. Although millions of individuals have undergone LASIK eye surgery since it…
Ectopia Lentis: Causes, Symptoms, and Management
Ectopia lentis is a term that holds a pivotal place within the realm of ophthalmology, shedding light on a unique condition that involves the lens of the eye. This condition, characterized by the displacement or dislocation of the lens from…
What Is Bullous Keratopathy and How to Manage It
What Is Bullous Keratopathy? Bullous keratopathy (BK) is a pathological condition characterized by the presence of fluid-filled blisters or “bullae” on the cornea, which is the clear front surface of the eye. The main underlying factor leading to the formation…
LumiThera Receives $2.3M NIH Grant for Dry AMD Trial
LumiThera has been granted a small business innovative research (SBIR) phase 2 grant from the National Institute of Health (NIH), totaling up to $2.3 million in funding over a span of 2 years. This NIH/NEI grant is geared towards supporting…
What Is Endophthalmitis and How to Manage It
What Is Endophthalmitis? Endophthalmitis is a rare but serious eye condition that can lead to vision loss if not promptly treated. This infection targets the interior structures of the eye, causing inflammation and potential damage. Understanding the symptoms, causes, treatment…
What Is Corneal Opacity? | OBN
Corneal opacity refers to the clouding or loss of transparency in the cornea, the clear, dome-shaped front part of the eye. It can significantly impair vision and lead to various visual disturbances. This comprehensive article aims to provide a detailed…