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Novartis to Halt Development of GA Gene Therapy

After observing discouraging phase 2 clinical data, Novartis has opted to terminate the clinical advancement of its geographic atrophy gene therapy candidate GT005, a product it acquired through the acquisition of Gyroscope Therapeutics. The announcement was officially disseminated by investment…

What Is Bull’s Eye Maculopathy and How to Manage It

What Is Bull’s Eye Maculopathy? Bull’s Eye Maculopathy is a specific form of retinal disease characterized by changes in the pigmentation of the macular region of the retina, often presenting as a ‘bull’s eye’ pattern. The macula is the central…

Best Treatment for Uveitic Macular Edema Identified

Repeat corticosteroid injections were found to be more effective in improving vision for individuals with persistent or recurrent uveitis-related macular edema compared to methotrexate or ranibizumab intravitreal injections, according to a recent clinical trial. The corticosteroid treatment exhibited superior results…

Iveric Bio’s Izervay for Geographic Atrophy Approved by FDA

Parent company Astellas Pharma announced that Iveric Bio has received FDA approval for Izervay (avacincaptad pegol intravitreal solution) to treat geographic atrophy (GA) secondary to age-related macular degeneration (AMD). As a new complement C5 inhibitor, Izervay stands out as the sole…

Tenpoint Therapeutics Launches with $70M Financing

Tenpoint Therapeutics, a biotechnology company focused on vision-restoring engineered cell-based therapeutics and in vivo reprogramming for degenerative ocular diseases, has announced its launch with a $70 million Series A financing. The funding will be used to develop the company’s regenerative…

Naegis Pharma Funds Novel Eye Drug

Naegis Pharmaceuticals Inc., a life sciences company specializing in inflammation and ophthalmology, announced the successful closure of a financing round to advance its lead compound, N0651, towards a Phase 2 clinical trial. This funding will support the compound’s progression through…

2023 Recap: Top 10 Contact Lenses and Technologies

In the ever-evolving landscape of ophthalmology, 2023 has proven to be a year of groundbreaking advancements in contact lens technology. From lenses that adapt to UV and temperature changes to intelligent lenses capable of diagnosing and treating glaucoma, the top…

Glaucomatous Optic Neuropathy & Latest Treatments

Glaucomatous optic neuropathy is characterized by progressive loss of retinal ganglion cells (RGCs) and their axons and leads to measureable structural and functional damage to the optic nerve, visual impairment, and blindness. The primary site of injury is thought to be…

SpyGlass Pharma Secures $90M in Funding

SpyGlass Pharma has successfully closed a Series C financing round, raising $90 million. RA Capital Management led the funding round, joined by existing investors New Enterprise Associates (NEA) and Vensana Capital, as well as new investors Samsara BioCapital and Vertex…

What Is Corneal Edema and How to Manage It

What Is Corneal Edema? Corneal edema refers to the swelling of the cornea, the transparent, dome-shaped layer at the front of the eye. This swelling typically results from an abnormal accumulation of fluid within the corneal layers, disrupting its usual…

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