Clinical Trial
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Minocycline Fails to Halt Progression of Dry AMD
In a recent phase II clinical trial conducted by the National Eye Institute (NEI), part of the National Institutes of Health, the antibiotic minocycline, known for its anti-inflammatory properties, was tested for its efficacy in slowing down the progression of…
Nicox Reveals Successful Phase 3 Glaucoma Eye Drop
Nicox SA announced the results of its pivotal Mont Blanc Phase 3 trial, which compared the efficacy of its novel nitric oxide-donating bimatoprost eye drop, NCX 470, against latanoprost in reducing intraocular pressure (IOP) in patients suffering from open-angle glaucoma…
Innovent’s nAMD Drug Succeeds in Phase 2 Trial
Innovent Biologics announced that its second Phase 2 clinical trial of efdamrofusp alfa (R&D code: IBI302), a high-dose recombinant human VEGFR-Fc-Human CR1 fusion protein injection, has achieved its primary endpoint in treating Chinese subjects with neovascular age-related macular degeneration (nAMD).…
Top 12 Gene Therapies for Eye Diseases and Blindness
In a groundbreaking era of medical research, scientists and clinicians are spearheading novel gene therapies that hold promise for transforming the landscape of eye disease treatment. These cutting-edge interventions address a spectrum of conditions ranging from Usher Syndrome and retinoschisis…
OcuTerra’s Nesvategrast Misses Mark in Diabetic Retinopathy Trial
OcuTerra Therapeutics announced the topline results from its phase 2 DR:EAM (Diabetic Retinopathy: Early Active Management) clinical trial, evaluating the efficacy of nesvategrast (OTT166). Nesvategrast, an innovative RGD integrin inhibitor formulated as an eye drop, was under investigation for its…
MediPrint Finalizes Glaucoma Contact Lens Study
MediPrint Ophthalmics has successfully completed its SIGHT-2 phase 2b study, showcasing the efficacy of its innovative product, LL-BMT1, against a control group using bimatoprost 0.01% ophthalmic solution. LL-BMT1, a preservative-free, weekly drug-eluting contact lens, utilizes the company’s 3D printing technology,…
Innovent’s Phase 3 TED Treatment Success in China
Innovent Biologics announced the successful achievement of the primary endpoint in the phase 3 registrational study, RESTORE-1, of IBI311 in China. This recombinant anti-insulin-like growth factor 1 receptor (IGF-1R) antibody marks a pivotal advancement in the treatment of thyroid eye…
Eversight Partners with Emmecell for Ocular Therapy Advances
Eversight, a leading non-profit dedicated to the restoration of sight through the recovery, processing, and distribution of corneal tissue, announced a strategic partnership with Emmecell Biotech, a biotechnology company focused on developing novel cell therapies for ocular diseases. This collaboration…
Dr. Arshad Khanani Joins Ophtea as Chief Medical Advisor
Opthea Limited announced Dr. Arshad M. Khanani, MD, MA, FASRS, as its new Chief Medical Advisor. Dr. Khanani, renowned in retina specialization and clinical research, brings a wealth of expertise from his tenure at Sierra Eye Associates and his academic…
Opthea Completes Enrollment for Wet AMD Trial
Opthea has reached a significant milestone in its quest to combat wet age-related macular degeneration (AMD) with the completion of patient enrollment in the COAST phase 3 pivotal clinical trial. The trial investigates sozinibercept (OPT-302), a promising vascular endothelial growth…